检索范围：
排序： 展示方式：
多功能结构设计与原位制造 Article
张岩, 张广玉, 乔菁, 李隆球
《工程（英文）》 2023年 第28卷 第9期 页码 58-68 doi: 10.1016/j.eng.2022.11.009
马建芳,曾爱萍,谢德辉,邱凤英,张宁,陈宏
《中国工程科学》 2003年 第5卷 第4期 页码 70-72
研究了丙酸睾丸酮治疗不稳定型心绞痛的疗效，给48例不稳定型心绞痛患者加用丙酸睾丸酮50 mg肌肉注射，每周2次，12周后观察临床疗效及血液指标变化，并与对照组比较。认为丙酸睾丸酮具有调脂、减少炎症反应及扩血管作用，能显著改善临床症状及预后。
固定化溶菌酶的氧化石墨烯/聚醚砜杂化超滤膜制备及抗菌性能研究
朱军勇,王琼柯,许欣,刘绰绰,刘金盾,张亚涛
《中国工程科学》 2014年 第16卷 第7期 页码 23-29
赵现立,刘朝阳,谭宏伟,张恩娣
《中国工程科学》 2015年 第17卷 第6期 页码 13-15
目的：观察稽留流产清宫术后服用屈螺酮炔雌醇片对减轻宫腔粘连发生的效果。两组患者均在清宫术前服用米非司酮片150 mg和米索前列醇片600 μg治疗，术后常规应用抗生素3天。观察组：清宫术后给予屈螺酮炔雌醇片，每天服用一片，连续3个周期，对照组：患者实施清宫术后不给予屈螺酮炔雌醇片治疗。结论：清宫术后口服屈螺酮炔雌醇片是减少稽留流产术后发生宫腔粘连的一种安全有效的方法。
用于锂离子电池的富醚/酯/氟黏结剂配方 Article
Xianqing Zeng, Donglin Han, Zeheng Li, Hongxun Wang, Gu Wu, Yong Deng, Kai Liu, Li Xie, Chengdu Liang, Min Ling, Yuchuan Huang
《工程（英文）》 2022年 第19卷 第12期 页码 199-206 doi: 10.1016/j.eng.2022.05.020
丹参酮IIA通过Beclin-1介导的自噬性凋亡抑制非小细胞肺癌 Article
白莎莎, 崔赛男, 温文浩, 梁丽娴, 白静, 林慧媛, 崔永飞, 杨蕾, 刘中秋, 郑远, 张荣
《工程（英文）》 2022年 第19卷 第12期 页码 128-138 doi: 10.1016/j.eng.2021.07.014
人体前列腺特异性抗原携带含酮基-脱氧壬酮糖酸的N-聚糖 Article
Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer
《工程（英文）》 2023年 第26卷 第7期 页码 119-131 doi: 10.1016/j.eng.2023.02.009
Ketodeoxynononic acid (Kdn) is a rather uncommon class of sialic acid in mammals. However, associations have been found between elevated concentrations of free or conjugated Kdn in relation to human cancer progression. Hitherto, there has been a lack of conclusive evidence that Kdn occurs on (specific) human glycoproteins (conjugated Kdn). Here, we report for the first time that Kdn is expressed on prostate-specific antigen (PSA) N-linked glycans derived from human seminal plasma and urine. Interestingly, Kdn was found only in an α2,3-linkage configuration on an antennary galactose, indicating a highly specific biosynthesis. This unusual glycosylation feature was also identified in a urinary PSA cohort in relation to prostate cancer (PCa), although no differences were found between PCa and non-PCa patients. Further research is needed to investigate the occurrence, biosynthesis, biological role, and biomarker potential of both free and conjugated Kdn in humans.
含硫醚和砜亚结构的新型芳香酰胺类衍生物的设计、合成及生物活性 Article
华学文, 刘南南, 周沙, 张蕾蕾, 殷昊, 王桂清, 范志金, 马翼
《工程（英文）》 2020年 第6卷 第5期 页码 553-559 doi: 10.1016/j.eng.2019.09.011
月经周期中免疫球蛋白G N-糖基化的周期性变化 Article
Julija Jurić, Hongli Peng, Manshu Song, Frano Vučković, Jelena Šimunović, Irena Trbojević-Akmačić, Youxin Wang, Jiaonan Liu, Qing Gao, Hao Wang, Qiaoyun Chu, Marija Pezer, Wei Wang, Gordan Lauc
《工程（英文）》 2023年 第26卷 第7期 页码 108-118 doi: 10.1016/j.eng.2022.10.020
Immunoglobulin G (IgG) is the most abundant plasma glycoprotein and a prominent humoral immune mediator. Glycan composition affects the affinity of IgG to ligands and consequent immune responses. The modification of IgG N-glycosylation is considered to be one of the various mechanisms by which sex hormones modulate the immune system. Although the menstrual cycle is the central sex hormone-related physiological process in most women of reproductive age, IgG N-glycosylation dynamics during the menstrual cycle have not yet been investigated. To fill this gap, we profiled the plasma IgG N-glycans of 70 healthy premenopausal women at 12 time points during their menstrual cycles (every 7 days for 3 months) using hydrophilic interaction ultra-performance liquid chromatography (HILIC-UPLC). We observed cyclic periodic changes in the N-glycosylation of IgG in association with the menstrual cycle phase and sex hormone concentration in plasma. On the integrated cohort level, the modeled average menstrual cycle effect on the abundance of IgG N-glycosylation traits was low for each trait, with the highest being 1.1% for agalactosylated N-glycans. However, intrapersonal changes were relatively high in some cases; for example, the largest difference between theminimum and maximum values during themenstrual cycle was up to 21% for sialylated N-glycans. Across all measurements, the menstrual cycle phase could explain up to 0.72% of the variation in the abundance of a single IgG glycosylation trait of monogalactosylation. In contrast, up to 99% of the variation in the abundance of digalactosylation could be attributed to interpersonal differences in IgG N-glycosylation. In conclusion, the average extent of changes in the IgG N-glycopattern that occur during the menstrual cycle is small; thus, the IgG N-glycoprofiling of women in large sample-size studies can be performed regardless of menstrual cycle phase.
标题 作者 时间 类型 操作
用于锂离子电池的富醚/酯/氟黏结剂配方
Xianqing Zeng, Donglin Han, Zeheng Li, Hongxun Wang, Gu Wu, Yong Deng, Kai Liu, Li Xie, Chengdu Liang, Min Ling, Yuchuan Huang
期刊论文
人体前列腺特异性抗原携带含酮基-脱氧壬酮糖酸的N-聚糖
Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer
期刊论文
DNAN的高级氧化过程研究
苏海磊, Christos Christodoulatos, Benjamin Smolinski, Per Arienti, Greg O´Connor, 孟晓光
期刊论文
京公网安备 11010502051620号
